Medications That May Impair Driving

Medical conditions and their associated functional losses may lead to a decline in ‘driving health’ and an increase in crash risk. The appropriate use of medications to control medical conditions and symptoms may preserve or restore functional ability. But certain medications when taken as prescribed also may impair a person’s ability to safely operate a motor vehicle. Researchers have identified such “potentially driver impairing” (PDI) medications by therapeutic class, by active ingredient, and by their brand/trade names.

PDI information was reviewed in a NHTSA-sponsored literature review Polypharmacy and Older Drivers, and through continuing analyses of administrative claims databases including ICD9-CM injury codes (E-codes) that establish associations between injuries in traffic crashes and the drugs prescribed at the time of the crash for the drivers of the involved vehicles.

To access information about PDI medications, please click on the graphic below to visit Roadwise Rx.

The video below provides an overview of PDI medications.